Rat small intestine muscle relaxation alkaloids from Orixa japonica leaves.

نویسندگان

  • S Funayama
  • R Tanaka
  • Y Kumekawa
  • T Noshita
  • T Mori
  • T Kashiwagura
  • K Murata
چکیده

Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first report of the isolation of eduline (2) from O. japonica.

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عنوان ژورنال:
  • Biological & pharmaceutical bulletin

دوره 24 1  شماره 

صفحات  -

تاریخ انتشار 2001